Dr Arun Krishnan is a consultant Neurologist at Prince of Wales Hospital. His research is at the forefront of a relatively new research field in human neurophysiology, studies of axonal excitability and its disorders. Measurements of excitability provide information regarding the activity of ion channels, energy-dependent pumps and ion exchange processes activated during impulse conduction. Abnormalities of ion channel function are a major factor in many neurological diseases, including peripheral neuropathy, motor neurone disease, multiple sclerosis and epilepsy. Excitability techniques are clinical methods of assessing nerve function, which are applied to patients with neurological disease.
In addition to investigating causes of neurological disease, Dr Krishnan also conducts clinical trials of new treatments for these conditions, based on the findings of his research. Dr Krishnan’s work is conducted in conjunction with research groups led by Professor Matthew Kiernan at the Prince of Wales Clinical School and Neuroscience Research Australia and Dr Cindy Lin in the Department of Exercise Physiology at UNSW.
He also works with extensive local, national and international collaborators who are involved in excitability research. Furthermore he is also interested in novel methods for diagnosing and treating neurological complications of systemic diseases, including diabetes, renal disease and cancer.