This project aims to assess the practical impact of Motor Neurone Disease (MND) on both patients and their family members. Cognitive ability and behavioural changes are measured in a longitudinal fashion after 6 and 12 months with the aim of investigating how these changes can affect disease progression, prognosis and provision of care. In conjunction the entire neural/motor axis in MND will be assessed using Transmagnetic Stimulation, peripheral axonal excitability studies and brain imaging techniques to examine how structural changes relate to everyday disability.
