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Halliday Group - Professor Glenda Halliday

Age-related neurodegenerative disorders are relentless progressive diseases, producing relatively rapid dependencies for care, and are therefore responsible for considerable health-related expenditures. No successful treatments are available for any of these disorders, largely because the mechanisms determining the highly selective patterns of neuron loss are poorly understood. Our research aims to identify the sequence of cellular changes occurring in neurodegenerative disorders for targeted interventions. We are particularly focussed on the earliest changes observed and on how such changes may be identified in clinical settings. Our research also focuses on understanding the influence of different genetic traits and protein abnormalities in these disorders.

Click here to access Prof Glenda Halliday's research papers:

Human Brain Tissue Group Meetings 2012

For more details go to our information page on the Human Brain Tissue Group Meetings.

NHMRC Senior Principal Research Fellow, NeuRA
Conjoint Professor, School of Medical Sciences, UNSW
Honorary Visiting Scientist, Westmead Hospital, Concord Hospital
T: +612 9399 1704
E: g.halliday@neura.edu.au

Prof Glenda Halliday is an internationally renowned expert in the pathogenesis of Parkinson’s disease and other neurodegenerative disorders. She received her degrees from the University of New South Wales and postdoctoral training at the Centre for Neuroscience, Flinders University of South Australia prior to returning to Sydney as an Australian Research Council Queen Elizabeth II Fellow. She has been a research fellow of the National Health and Medical Research Council of Australia since then and one of the senior scientists at Neuroscience Research Australia (joined in 1993). She has published over 300 research articles and two books, the most recent on Parkinson’s disease, and was president of the Australian Neuroscience Society from 2006-2007.

Her research has highlighted broader pathological involvement in Parkinson's disease and in dementia associated with Lewy bodies. In particular, her PhD and subsequent postdoctoral work on the anatomy and pathology of dopaminergic systems and other brainstem monoaminergic systems in controls and patients with Parkinson's disease is highly cited, having revealed that more than the dopamine system was damaged in this disorder. Her subsequent research has focused on understanding how this occurs with the suggestion that humoral immunity is involved. Her pathological work on dementia with Lewy bodies has been incorporated into highly cited research criteria for the diagnosis of this disorder, highlighting the association between Lewy body deposition and visual hallucinations rather than a loss of function. In the non-Alzheimer frontotemporal dementias her laboratory developed a disease severity staging scheme to assist with further research, and in association with Prof Hodges and colleagues developed this scheme into a simple tool for clinical use. Her current work is focusing on how proteins identified through genetic studies are involved in neurodegenerative processes.

Alzheimer's disease

Dr Claire Shepherd, NeuRA Senior Research Officer & Sydney Brain bank Manager, assists with overseeing these projects

2011 Research Projects:

Frontotemporal dementia and related disorders

2011 Research Projects:

Memory dysfunction within limbic cortices - It is apparent that the complexities of the memory dysfunction seen in different neurodegenerative diseases cann

Parkinson's disease and related syndromes

Dr Yue Huang, NeuRA Senior Research Officer, assists with overseeing these projects

Research team 
Prof Glenda Halliday's picture
Professor Glenda Halliday
NHMRC Senior Principal Research Fellow, NeuRA
Conjoint Professor, School of Medical Sciences, UNSW
T: +612 9399 1704
E: g.halliday@neura.edu.au
Dr Scott Kim's picture
Dr Scott Kim
Senior Research Officer
Conjoint Senior Lecturer, School of Medical Sciences, UNSW
T: +612 9399 1084
E: w.kim@neura.edu.au
Dr Yue Huang's picture
Dr Yue Huang
Senior Research Officer
T: +612 9399 1041
E: y.huang@neura.edu.au
Ms Heidi Cartwright's picture
Heidi Cartwright
P/T Senior Research Assistant
T: +612 9399 1823
E: h.cartwright@neura.edu.au
Dr Rachel Tan's picture
Dr Rachel Tan
Research Officer
T: +612 9399 1151
E: r.tan@neura.du.au
Amanda Gysbers's picture
Amanda Gysbers
Research Assistant
T: +612 9399 1802
E: a.gysbers@neura.edi.au
Lauren Bartley's picture
Lauren Bartley
Research Assistant
FRONTIER Biomarkers in FTD Study Coordinator
T: +612 9399 1287
E: l.bartley@neura.edu.au
Ms Francine Carew-Jones's picture
Francine Carew-Jones
Research Assistant
T: +612 9399 1802
E: f.carew-jones@neura.edu.au
Tony Hsiao's picture
Tony Hsiao
Research Assistant
Claire Stevens's picture
Claire Stevens
PhD Student
T: +612 9399 1802
E: c.stevens@neura.edu.au
Marlene Shibata's picture
Marlene Shibata
Research Assistant
T: +612 9382 2449
E: m.shibata@neura.edu.au
Lisa Mak's picture
Lisa Mak
PhD student
T: +612 9399 1106
E: l.mak@neura.edu.au

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