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Paxinos Group - Scientia Professor George Paxinos AO

Brain researchers, no less than geographers, need maps and coordinate systems to navigate the brain and communicate their observations to each other. On a map of the brain, we can superimpose types of neurons, neurotransmitters, enzymes, connectivity, and functional data. We are now constructing the new generation of brain and spinal cord maps to assist in (a) the study of animal models of disease, such as Parkinson’s disease, amyotrophic lateral sclerosis (ALS), and Alzheimer’s disease; (b) the interpretation of human and non-human MRI and diffusion tensor imaging (DTI) data, and (c) improving the accuracy of interventions on the human brain.

NHMRC Australia Fellow, NeuRA
Visiting/Conjoint Professor of Psychology and Medical Sciences, UNSW

George Paxinos completed his BA at The University of California at Berkeley, his PhD at McGill University, and spent a postdoctoral year at Yale University. He and Charles Watson are the authors of The Rat Brain in Stereotaxic Coordinates. With over 61,000 citations over its 7 Editions (March 2014), this is the third most cited book in science after Molecular Cloning and the Diagnostic and Statistical Manual of Mental Disorders. George Paxinos has also published another 45 books on the structure of the brain of humans and experimental animals. His work was recognised by an AO, Ramaciotti Medal, Humboldt Prize, and a $4 million NHMRC Australia Fellowship in 2009. He is a Fellow of the Academy of Social Sciences in Australia and a corresponding member of the Academy of Athens.

Prof Paxinos's most significant atlases and books

The Paxinos and Watson Collaboration

Nissl and AChE Staining Protocols for Beginners

The Australian Research Council Centre of Excellence for Integrative Brain Function

Brain Dialogue: MRI/DTI Rat Brain Atlas

Pictures of Paxinos

A 3D Cross-Modality Atlas of the Human Brainstem for Scientists and Clinicians

In collaboration with MR expert Dr Mark Schira at UOW, we are determining the variability of human brainstem structures in order to produce an electronic atlas of the human brainstem, combining in

Enhancing the Repair Potential of Precursor Cells in Neurodegeneration

This project aims at providing a better understanding of the anatomical aspects of adult neurogenesis and at finding effective ways to stimulate neuronal regeneration in the brain.

Organisation of Projections to and from the spinal cord

This work is focused on mapping projections from hindbrain nuclei to the spinal cord in unprecedented detail.

Substantia Nigra Dopaminergic Neuron Populations as Defined by Genetic Microdissection

We use a genetic microdissection technique to characterize each of the six segmental populations of the substantia nigra dopaminergic neurons so that their differential role in Parkinson’s disease

Research team 
Scientia Prof George Paxinos AO's picture
Scientia Professor George Paxinos AO
NHMRC Australia Fellow, NeuRA
Visiting/Conjoint Professor of Psychology and Medical Sciences, UNSW
Prof Charles Watson's picture
Professor Charles Watson
Distinguished Professor in the Faculty of Health Sciences, Curtin University
Lead for the Neurosciences and the Senses Health Network, Western Australian Department of Health