Paxinos Group banner

Paxinos Group - Scientia Professor George Paxinos AO

Brain researchers, no less than geographers, need maps and coordinate systems to navigate the brain and communicate their observations to each other. On a map of the brain, we can superimpose types of neurons, neurotransmitters, enzymes, connectivity, and functional data. We are now constructing a new generation of brain and spinal cord maps to assist in (a) the study of animal models of disease, such as Parkinson’s disease, amyotrophic lateral sclerosis (ALS), and Alzheimer’s disease; (b) the interpretation of human and non-human MRI and diffusion tensor imaging (DTI) data, and (c) improving the accuracy of interventions in the human brain.

NHMRC Senior Principal Research Scientist, NeuRA
Conjoint Scientia Professor of the School of Medical Sciences, UNSW

Prof George Paxinos completed his BA at The University of California at Berkeley, his PhD at McGill University, and spent a postdoctoral year at Yale University. He and Prof Charles Watson are the authors of The Rat Brain in Stereotaxic Coordinates. With over 50,000 citations across its seven Editions (March 2014), it is the third most cited book in science after Molecular Cloning and the Diagnostic and Statistical Manual of Mental Disorders. Prof Paxinos has also published another 45 books on the structure of the brain of humans and experimental animals, his most recent being MRI/DTI Atlas of the Rat Brain. His work was recognised by an AO, Ramaciotti Medal, Humboldt Prize, a $4 million NHMRC Australia Fellowship and the NSW Premier's Prize for Excellence in Medical Biological Sciences in 2015. He is a Fellow of the Australian Academy of Science, the Academy of Social Sciences in Australia and a corresponding member of the Academy of Athens. His novel Κατ’ Εικόνα (In His Image) was published in Greek in 2015 (English version pending).

Prof Paxinos's most significant atlases and books

The Paxinos and Watson Collaboration

Nissl and AChE Staining Protocols for Beginners

The Australian Research Council Centre of Excellence for Integrative Brain Function

Brain Dialogue: MRI/DTI Rat Brain Atlas

Pictures of Paxinos

A 3D Cross-Modality Atlas of the Human Brainstem for Scientists and Clinicians

In collaboration with MR experts Al Johnson (a Professor of Radiology, Physics, and Biomedical Engineering from Duke University) and Dr Mark Schira at the University of Wollongong, we are constructing

Construction of a web-based 3D mouse brain atlas

Prof Paxinos and Dr Schofield have produced very high resolution images of the adult and postnatal day 6 mouse brain at 40 micron intervals in 3 planes of section corresponding to The Mouse Brain i

High Resolution MRI Atlas of the Rat Brain

The most recent project completed by Paxinos and Watson was the publication, in book form, of the first of a new generation of atlases exploiting the power of magnetic resonance histology, diffusion t

Organisation of Projections to and from the spinal cord

Dr Huazheng (Andy) Liang has been investigating the pathways that connect the brain to the spinal cord for the past 9 years.

Towards quantitative cell type-based mapping of the whole mouse brain

Prof Paxinos is joining Assoc Prof Pavel Osten at Cold Spring Harbour Laboratory in developing a method to rapidly determine the identity and cell composition of any region within the whole mouse brai

Research team 
Scientia Prof George Paxinos AO's picture
Scientia Professor George Paxinos AO
NHMRC Senior Principal Research Scientist, NeuRA
Conjoint Scientia Professor of the School of Medical Sciences, UNSW
Prof Charles Watson's picture
Professor Charles Watson
Distinguished Professor in the Faculty of Health Sciences, Curtin University
Lead for the Neurosciences and the Senses Health Network, Western Australian Department of Health