Brain control of movement

RESEARCH STUDY

How the brain controls movement

We are looking for volunteers to participate in a study of how the brain controls movement and how the brain compensates when there is damage to brain regions that control movement.

To participate, you must be aged 50-70 years with no neurological condition or mental illness and live in either the Sydney or Adelaide metropolitan region.

We are also looking for individuals with:

  • restless legs syndrome
  • Parkinson’s disease

The study will involve an ultrasound of your head to obtain a picture of your brain. A neurologist will examine your movements and you will be asked to complete a short series of tests to assess thinking and memory. Some volunteers will then be asked to undergo magnetic resonance imaging (MRI) and magnetic stimulation of the brain. Both procedures are safe, painless, and are routinely used in clinical and research settings.

 

See what’s going on at NeuRA

FEEL THE BUZZ IN THE AIR? US TOO.

‘Progressive. Incurable. Terminal. Nothing matters… I am going to die.’

‘There are days that I just cry like a baby. I’m meant to be the provider, the strong one. No son should have to change the underwear of their 57 year old father.’ Shin Liu is a man you want to know... kind, articulate and with love in his heart. At 57 years old however, Shin has planned his funeral. Two years ago, Shin was diagnosed with motor neurone disease (MND). Unlike many cancers or heart disease, there is not a single thing the medical profession can do to stop MND. This excruciating disease twists and contorts the human body in the most horrific way, and it quickly destroys the ability to move, speak, swallow and breathe. Life expectancy post diagnosis is 2.5 years. But NeuRA researchers are making exciting progress toward it's defeat. After years of meticulous research, we've learnt that in more than 90% of MND cases a protein called TDP-43 is responsible for the changes in motor neurones. In pre-clinical (non-human) trials, we have found that this protein can be controlled by a specially engineered peptide sequence (i.e. medication) which has the potential to stop MND in its tracks. But here is the most exciting development… we are observing improvements in movement, behaviour and memory upon administering this medication! This is innovative, ground-breaking research and we need your help to accelerate this research, which will in time enable clinical trials in people living with MND. Will you support or research today?
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