Five teens in a row, chins resting in hands

Brain development in children and adolescents

RESEARCH STUDY

How do children’s brains develop and change as they grow older? We would like your help to study this using Magnetic Resonance Imaging (MRI).

WHO CAN PARTICIPATE? Healthy children and adolescents aged between 6-18 years.

WHY PARTICIPATE? To help us to understand how the brain changes from childhood to adulthood. You will be contributing to research, which may help people with mental disorders such as autism and schizophrenia.

You will be reimbursed for your travel and parking costs to the clinic and every participant will receive two movie tickets and a picture of their brain to take home with them!

For more information visit Prof Rhoshel Lenroot’s page.

Thinking about participating? Click here to find out what it’s like to have an MRI.

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FEEL THE BUZZ IN THE AIR? US TOO.

Caress the Detail: A Comprehensive MRI Atlas of the in Vivo Human Brain

This project aims to deliver the most comprehensive, detailed and stereotaxically accurate MRI atlas of the canonical human brain. In human neuroscience, researchers and clinicians almost always investigate images obtained from living individuals. Yet, there is no satisfactory MRI atlas of the human brain in vivo or post-mortem. There are some population-based atlases, which valiantly solve a number of problems, but they fail to address major needs. Most problematically, they segment only a small number of brain structures, typically about 50, and they are of limited value for the interpretation of a single subject/patient. In contrast to population-based approaches, the present project will investigate normal, living subjects in detail. We aim to define approximately 800 structures, as in the histological atlas of Mai, Majtanik and Paxinos (2016), and, thus, provide a “gold standard” for science and clinical practice. We will do this by obtaining high-resolution MRI at 3T and 7T of twelve subjects through a collaboration with Markus Barth from the Centre for Advanced Imaging at the University of Queensland (UQ). The limited number of subjects will allow us to image each for longer periods, obtaining higher resolution and contrast, and to invest the required time to produce unprecedented detail in segmentation. We will produce an electronic atlas for interpreting MR images, both as a tablet application and as an online web service. The tablet application will provide a convenient and powerful exegesis of brain anatomy for researchers and clinicians. The open access web service will additionally provide images, segmentation and anatomical templates to be used with most common MR-analysis packages (e.g., SPM, FSL, MINC, BrainVoyager). This will be hosted in collaboration with UQ, supporting and complementing their population-based atlas.
PROJECT