Woman has a sore back

Back Pain

RESEARCH STUDY

Back pain is very common and is the leading cause of disability worldwide. It can range from a dull, constant ache to a sudden, sharp pain that makes it hard to move.

About Our Research
Our research is directed towards first understanding why some people with a low back pain don’t recover and develop longer term, or chronic, low back pain. We are developing and testing new interventions to treat those that already have chronic pain and approaches to prevent people from developing chronic pain in the first place. We are proposing that treatments targeting the brain in addition to traditional treatments might be more effective for reducing chronic low back pain. We are also proposing that rather than waiting to treat patients who already have chronic low back pain, much better outcomes are likely to be achieved if we intervene early to reduce the risk of developing chronic low back pain after an acute episode.

To Participate In Our Research

Please contact the Pain@NeuRA research team:
email: pain@neura.edu.au
Phone: 02 9399 1627

See what’s going on at NeuRA

FEEL THE BUZZ IN THE AIR? US TOO.

Caress the Detail: A Comprehensive MRI Atlas of the in Vivo Human Brain

This project aims to deliver the most comprehensive, detailed and stereotaxically accurate MRI atlas of the canonical human brain. In human neuroscience, researchers and clinicians almost always investigate images obtained from living individuals. Yet, there is no satisfactory MRI atlas of the human brain in vivo or post-mortem. There are some population-based atlases, which valiantly solve a number of problems, but they fail to address major needs. Most problematically, they segment only a small number of brain structures, typically about 50, and they are of limited value for the interpretation of a single subject/patient. In contrast to population-based approaches, the present project will investigate normal, living subjects in detail. We aim to define approximately 800 structures, as in the histological atlas of Mai, Majtanik and Paxinos (2016), and, thus, provide a “gold standard” for science and clinical practice. We will do this by obtaining high-resolution MRI at 3T and 7T of twelve subjects through a collaboration with Markus Barth from the Centre for Advanced Imaging at the University of Queensland (UQ). The limited number of subjects will allow us to image each for longer periods, obtaining higher resolution and contrast, and to invest the required time to produce unprecedented detail in segmentation. We will produce an electronic atlas for interpreting MR images, both as a tablet application and as an online web service. The tablet application will provide a convenient and powerful exegesis of brain anatomy for researchers and clinicians. The open access web service will additionally provide images, segmentation and anatomical templates to be used with most common MR-analysis packages (e.g., SPM, FSL, MINC, BrainVoyager). This will be hosted in collaboration with UQ, supporting and complementing their population-based atlas.
PROJECT