Breathing is a complex motor task that needs to be coordinated at all times while we eat, speak, exercise and even during sleep. The breathing muscles are controlled automatically from the brainstem during normal breathing but can also be controlled voluntarily from the motor cortex.
The way these two drives to the breathing muscles interact is still not well understood. While there is some evidence that there are at least two independent pathways, and that integration of the pathways occurs at the spinal cord, there is some uncertainty about whether these pathways may have some interaction in the brainstem.
Our overall goal is to determine the role of neural drive in impairments of respiratory muscle function in older adults (over 65 years), people with chronic obstructive pulmonary disease (COPD), spinal injury or obstructive sleep apnoea (OSA).
Epigenetics is the study of how our environment influences the expression of our genes. My group has found a link between early life experiences and attention. Exposure to traumatic experiences in the early stages of life, including abuse or neglect, parental divorce or mental illness, and poverty, are known to influence the development of some mental illnesses. These early experiences also […]