Dementia is a group of brain disorders that affect a person’s memory, thinking and ability to interact socially. It is caused by damaged nerve cells that may occur in several areas of the brain. As a result, people experience dementia differently, depending on which area of their brain is affected. The dementia types are classified in a variety of ways, often according to what they have in common or whether they worsen over time (progressive dementias).
Some dementias, such as those caused by a reaction to medications or an infection, are reversible with treatment.
Types of dementias that are not reversible and worsen over time include:
For many older adults, driving is essential for independence and participation in life. However, ageing is associated with a range of physical, sensory, and cognitive changes, some of which can influence driving safety. Neurodegenerative conditions such as dementia can progress very gradually, and regular monitoring is required to identify the point at which driving becomes unsafe. Current methods of monitoring road safety for older drivers relies on regular reviews with doctors or expensive and stressful driving tests. These methods are resource intensive and inefficient. Thus, there is a need for more cost-effective and less invasive ways of monitoring road safety for older drivers. The Changing Memory, Technology and Driving study (MemTech) will investigate whether a dashboard camera and a GPS data logger can be used to accurately measure changes in safety during an older driver’s everyday driving trips. The study will involve older drivers who are experiencing changes in their thinking and memory or early stages of dementia, as well as older drivers without any cognitive difficulties. This will allow data to be compared across the two groups to determine whether the in-vehicle GPS devices can detect changes in driver safety associated with cognitive change. If it can, this will provide valuable research data for the future development of accurate in-vehicle monitoring systems for older driver safety.
This research is being funded by the Office of Road Safety.
If you would like to take part in this research study, please contact
Ms Abirami Raveendran
Phone: (02) 9399 1058
Researchers at Neuroscience Research Australia (NeuRA) and University of New South Wales (UNSW) are inviting people who have noticed changes in their memory or thinking, or are diagnosed with Mild Cognitive Impairment (MCI), to participate in a voluntary research trial investigating dementia risk reduction.
What is the MyCOACH Trial about?
This research aims to test the effectiveness of an e-learning and behaviour change course designed to support healthy brain ageing and reduce risk of dementia. The course is tailored for people experiencing changes or concerns in thinking, memory or cognition. The trial runs for 12 weeks, with a follow up 1 year afterwards.
What is involved in this research trial?
Interested volunteers will be asked to complete some eligibility checks to confirm this study is a good match. If you decide to take part you would be placed into one of two groups. To ensure the research is fair and unbiased, the group is chosen randomly – like pulling names from a hat.
Control group: Participants will receive information about cognitive health and risk factors for dementia. This group is important to be able to measure the effectiveness of the research. At the end of the study, access to the full MyCOACH e-learning course will be provided.
You may be eligible to participate in the MyCOACH Trial if you:
Expressions of interest
If you are interested, or know someone who might be, please register below or contact us directly.
Research Team Contact
Phone: (02) 9399 1815
There is increasing evidence to show that intergenerational interaction is beneficial for older adults and children alike. Higher levels of social engagement in older adults have been associated with better physical and cognitive function and wellbeing. Time spent with older adults has been linked to enhanced social and personal skills in children. However, familial intergenerational interaction is falling despite rising numbers of community-based older adults. In Australia alone approximately 15% of the total population are aged 65 and over, up from 5% in the 1920s and estimated to increase to 22% (8.8 million) in the next 30-40 years. Employment and economic factors drive greater geographical mobility of working age adults, resulting in increased separation from older family members with 40% of Australians aged 75-84 and 51% of those 85 and over living alone. Recent television series in Australia and the United Kingdom, have raised awareness and enthusiasm for intergenerational activities as an opportunity that could be realised within communities. However, while intergenerational programs are gaining in popularity globally, evidence for best practice in this area remains scarce.
This project will build and pilot a novel, evidence-based, co-designed Intergenerational Program Development toolkit targeted for community use and tailored to an Australian environment.
Interested in volunteering?
The General Practice Knowledge Translation (GP-KT) project is an online survey designed to help us understand what people already know about dementia risk and dementia risk reduction in frontline healthcare settings.
In particular we are keen to understand the barriers that might delay or prevent dementia risk reduction activities so that we can work to reduce these over time.
At the moment we are recruiting Australian General practitioners and their teams. International versions are the survey are also in development.
It is estimated that 1.2 million Australians are currently caring for someone with dementia. Caring for somebody with dementia can become more complicated by the presence of behavioural problems (e.g. depression, anxiety, apathy, aggression) in the person with dementia. These behavioural problems can contribute significantly to carer burden and distress. This study aims to improve our understanding of how interactions between the carer and the care-recipient affect behavioural problems in dementia. A better understanding of these interactions will help us develop programmes which can be used to assist the carer and those suffering from dementia to minimise the negative impact of problem behaviours in dementia.
Rates of behavioural and psychological symptoms of dementia (BPSD) amongst people living in residential aged care facilities (RACF) are high. Over 90% of Australian aged care residents exhibit clinically significant BPSD. Physical aggression, agitation and disinhibition, especially when severe, are difficult to manage and can put patients, carers and other residents at risk. Management of BPSD has recently become a focus of attention for the Australian Government, especially in relation to inappropriate overprescribing of antipsychotics. The discrepancy between international and national recommendations and the continued over-prescription of medication to manage BPSD must be addressed. Australia urgently needs better programs to support RACF to implement non-pharmacological, cost-effective management programs.
The NHMRC Dementia Centre for Research Collaboration (DCRC) was established in 2006 under the Australian Government’s Dementia Initiative. DCRC projects are diverse and map onto the priorities of the NHMRC National Network for Dementia Research (NNIDR). A key focus is applied research on topics meaningful to people with dementia and their family carers.
There are three DCRC hubs located at UNSW, NeuRA and QUT, respectively. The three-hub framework aims to grow partnerships and strengthen ties with consumers and service providers, Dementia Training Australia and Dementia Support Australia in order to progress prevention, assessment, care and translation of knowledge into everyday practice, as well as building the next generation of dementia researchers.
The primary focus of the DCRC NeuRA hub is risk reduction and prevention including individual, community and population-based interventions targeting lifestyle risk factors for dementia.
The flagship project of the DCRC NeuRA hub is the International Research Network on Dementia Prevention (IRNDP). Founded in 2017, the IRNDP is a multinational network bringing together researchers who are working to reduce the risk of dementia across the world. For more information on the network, visit the IRNDP website, including news and updates, an evidence hub on cohort studies, an evidence synthesis on clinical trials, and information on how to join.
The DCRC is funded by the National Health and Medical Research Council.
The Centre of Research Excellence in Cognitive Health focuses on the integrally linked areas of optimising cognitive health and the prevention of cognitive decline.
The centre aims to:
The CRE Cognitive Health led by Professor Kaarin Anstey is a collaboration between Chief and Associate Investigators from the Australian National University, University of Melbourne, University of New South Wales, Australian Catholic University, Baker IDI Heart and Diabetes Institute and University of Exeter.
The CRE Cognitive Health is funded by the National Health and Medical Research Council.
Globally, dementia cases are increasing at a rate of 21 per cent annually, and most of these are occurring in low to middle-income countries. With no cure for neurodegeneration or the diseases that cause dementia, there is an urgent need to link both knowledge translation and researchers more closely together in a global effort to tackle prevention more effectively.
Founded in 2017, the International Research Network on Dementia Prevention (IRNDP) is a multinational network bringing together researchers who are working to reduce the risk of dementia across the world.
IRNDP aims to:
The goals of the IRNDP have particular relevance in low- to middle-income (LMIC) countries as exposure to lifestyle and clinical risk factors becomes more common as LMIC economies grow.
While there are many current overlapping public health, patient, research, policy and practice initiatives aimed at prevention or treatment of dementia, IRNDP is the first single collaborative network of researchers to focus attention on prevention that is truly global.
IRNDP is chaired by Professor Kaarin Anstey and is a project of the Dementia Centre for Research Collaboration funded by the NHMRC National Institute for Dementia Research (NNIDR).
The Dementia Risk Factors and Assessment (DemRisk) program involves over ten years of research performed by the Anstey group on the identification and assessment of risk factors for Dementia.
The DemRisk program includes:
Read Professor Kaarin Anstey and Dr Ruth Peters’ recent invited commentary on second-hand smoke as an under-recognised risk factor for cognitive decline here. You can also watch Professor Anstey’s NeuRAtalk on ageing well to reduce your risk of dementia here.
Each year the number of older people undergoing surgery increases. Although evidence is well established that older age and frailty are associated with greater risk of poorer postoperative outcomes, there is little evidence to date to establish whether outcomes can be improved through geriatric intervention.
This research program explores the influence of dementia on the pattern of hospital admissions, clinical care, health outcomes and economic costs of older people with an injury-related hospitalisation. It provides data on the impact of injury on a person with dementia and the health system more generally.
The IFOCIS study aims to determine the ability of an individualised exercise and home hazard reduction program to reduce the rates of falls in older people living in the community with cognitive impairment or dementia. To do this, we have two groups– an ‘intervention’ group and a ‘control’ group. The Intervention program involves: an exercise program and a home hazard reduction program delivered by experienced therapists tailored to the participant’s cognitive and physical abilities. Carers are an integral part of the intervention team, as some participants require supervision for exercise sessions. We work with carers to help them understand how to get the best from the participant they are caring for, in terms of their ‘functional cognition’, completing the exercises and preventing falls.
Taking this individual approach means that participants can have very different cognitive abilities and still be included in our study. No other study has done this to date.
All participants will undergo an assessment at baseline with re tests at 6 and 12 months to compare each of these groups on things like strength & balance. The primary outcome is the rate of falls during the 12 month study period which is collected using falls diaries on a monthly basis.
Recruitment for this project is now complete. We are in the process of analysing the data and submitting this work for publication. We hope to have results available soon, please visit again for an update.
Falls and functional decline are common in people with dementia. Falls are more likely to result in injury, death and institutionalisation when compared to older people without dementia. There is limited evidence that falls can be prevented in people with dementia. Strategies aimed at maintaining independence and preventing decline and falls are urgently needed. This research will a) further our understanding of fall risk and functional decline and b) explore novel fall and decline prevention programs, including the use of technology in older people with dementia.
NeuRA’s Dr Moyra Mortby presented at Uniting War Memorial Hospital’s free seminar on Healthy Brains this week. Dr Mortby shared her research into the neuropsychiatric symptoms of dementia. These are the challenging behaviours associated with dementia such as delusions, sleep disturbances, anxiety and agitation. “Neuropsychiatric symptoms are a diverse group of non-cognitive symptoms of dementia that are characterised by disturbed […]