In addition to being caused by overt muscle damage, muscle pain (myalgia) more often develops from the demand for recurrent isometric muscular contractions involved in repetitive activity.
Characteristically, there is increased ‘muscle tone’, mild to severe pain, tender areas of hypersensitivity to mechanical stimulation in the muscle and spread of this hypersensitivity to surrounding muscles, each of which can affect the performance of synergist muscles.
However, the mechanisms by which acute muscle pain becomes pathological are yet to be understood. One idea relies on changes in muscle spindles, which are highly sensitive stretch receptors located in skeletal muscles throughout the body. Muscle spindles are unusual sensory organs in that they have their own motor innervation – fusimotor motoneurones – which can modulate the sensitivity of muscle spindles to static and dynamic muscle stretch and thereby influence their capacity to encode changes in muscle length and hence the sensory feedback they provide.
On August 11 2019, 54 people took on the City2Surf for Neuroscience Research Australia (NeuRA). The event is the world’s largest fun run with 80,000 participants taking on the 14km course, which stretches from Hyde Park in central Sydney to the iconic Bondi Beach. NeuRA thanks all of its fundraisers, who raised an incredible $30,903. This funding will further NeuRA’s […]