NeuRA Magazine #22

WHAT’S IN THIS ISSUE?

In the Spring 2017 issue we are reminded about the importance of research and the legacy we can leave by volunteering, not just during our life, but also on our passing. NeuRA is home to the Sydney Brain Bank, where our scientists work in conjunction with researchers around the world to provide critical tissue samples required for research into Alzheimer’s and other disorders of the brain. We chat with Associate Professor Melissa Green about her work on the risk factors for mental illness, and also take a look into the important work understanding the risk of falls in people with Parkinson’s Disease with members of the Falls, Balance and Injury group. We also recap the launch of the Child Safety Good Practice Guide.

To read the PDF click here.

 

Sydney Science Festival comes to NeuRA

 

Are you getting enough sleep?

 

Leaving a Legacy of Discovery

See what’s going on at NeuRA

FEEL THE BUZZ IN THE AIR? US TOO.

Caress the Detail: A Comprehensive MRI Atlas of the in Vivo Human Brain

This project aims to deliver the most comprehensive, detailed and stereotaxically accurate MRI atlas of the canonical human brain. In human neuroscience, researchers and clinicians almost always investigate images obtained from living individuals. Yet, there is no satisfactory MRI atlas of the human brain in vivo or post-mortem. There are some population-based atlases, which valiantly solve a number of problems, but they fail to address major needs. Most problematically, they segment only a small number of brain structures, typically about 50, and they are of limited value for the interpretation of a single subject/patient. In contrast to population-based approaches, the present project will investigate normal, living subjects in detail. We aim to define approximately 800 structures, as in the histological atlas of Mai, Majtanik and Paxinos (2016), and, thus, provide a “gold standard” for science and clinical practice. We will do this by obtaining high-resolution MRI at 3T and 7T of twelve subjects through a collaboration with Markus Barth from the Centre for Advanced Imaging at the University of Queensland (UQ). The limited number of subjects will allow us to image each for longer periods, obtaining higher resolution and contrast, and to invest the required time to produce unprecedented detail in segmentation. We will produce an electronic atlas for interpreting MR images, both as a tablet application and as an online web service. The tablet application will provide a convenient and powerful exegesis of brain anatomy for researchers and clinicians. The open access web service will additionally provide images, segmentation and anatomical templates to be used with most common MR-analysis packages (e.g., SPM, FSL, MINC, BrainVoyager). This will be hosted in collaboration with UQ, supporting and complementing their population-based atlas.
PROJECT