NeuRA Magazine #22

Dementia Research

PREVALENCE OF DEMENTIA IN INDIGENOUS COMMUNITIES

Research led by Prof Tony Broe and Dr Kylie Radford has highlighted the high prevalence of dementia, particularly Alzheimer’s disease, in Aboriginal communities. We are working towards understanding the causes of cognitive decline and dementia, building capacity in dementia care and supporting Aboriginal family carers, and developing culturally appropriate strategies to promote healthy brain ageing.

The next decade will see a dramatic increase in the number and proportion of older people within the Aboriginal and Torres Strait Islander population. Close to 80% of these older people live in regional and urban parts of Australia (a third in our major cities). Recently, the Koori Growing Old Well Study (KGOWS) has shown that dementia prevalence in Aboriginal Australians across NSW is three times higher than the overall Australian population, at ages 60 years and older.

What is it that helps one person age successfully, and causes another to develop age-related diseases like dementia? Scientifically, we know too little about normal ageing and what factors influence some people, and not others, to develop diseases that affect the brain. Only by studying healthy elderly people, as well as those with problems, can we know what normal ageing looks like and learn more about staying healthy as we age. In collaboration with our Aboriginal community partners, our rigorous population- based approach allowed us to accurately assess the prevalence of dementia, not just those already ‘in the system’ and seeking treatment or care.

NeuRA’s Aboriginal health and ageing team, with collaborators, are now conducting a follow-up study (KGOWS-II) to determine the social and biomedical risk and protective factors for dementia across the lifespan. In 2016, NeuRA also initiated the Koori Active and Healthy Ageing Project. This research will develop effective, culturally appropriate, and accessible strategies to promote vitality and healthy brain ageing and prevent dementia in Aboriginal communities. This research is supported by NeuRA’s ongoing Koori Dementia Care Project, which aims to build capacity in dementia understanding and care with Aboriginal community controlled and mainstream service providers.

As one older Aboriginal participant observed: “Healthy ageing is your mind staying young”.

See what’s going on at NeuRA

FEEL THE BUZZ IN THE AIR? US TOO.

The cold case of schizophrenia - broken wide open!

‘It is like they were miraculously healed!’’ Schizophrenia is diagnosed by clinical observation of behaviour and speech. This is why NeuRA researchers are working hard to understand the biological basis of the illness. Through hours of work and in collaboration with doctors and scientists here and around the world, NeuRA has made an amazing breakthrough. For the first time, researchers have discovered the presence of antibodies in the brains of people who lived with schizophrenia. Having found these antibodies, it has led NeuRA researchers to ask two questions. What are they doing there? What should we do about the antibodies– help or remove them? This is a key breakthrough. Imagine if we are treating schizophrenia all wrong! It is early days, but can you imagine the treatment implications if we’ve identified a new biological basis for the disease? It could completely change the way schizophrenia is managed, creating new treatments that will protect the brain. More than this, could we be on the verge of discovering a ‘curable’ form of schizophrenia? How you can help We are so grateful for your loyal support of schizophrenia research in Australia, and today I ask if you will consider a gift today. Or, to provide greater confidence, consider becoming a Discovery Partner by making a monthly commitment. We believe there is great potential to explore these findings. Will you help move today’s breakthrough into tomorrow’s cure? To read more about this breakthrough, click ‘read the full story’ below. You are also invited to read ‘Beth’s story’, whose sweet son Marcus lived with schizophrenia, by clicking here.
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