NeuRA Magazine #26

News

NOVEL TREATMENT FOR INFLAMMATION INDUCED DEPRESSION

Dr Adam Walker recently joined NeuRA as a Research Fellow and Senior Lecturer at the UNSW School of Psychiatry to lead key projects investigating the effects of neuro inflammation on neuropsychiatric disorders. Dr Walker’s research programs will revolve around the idea that the immune system and the brain talk to each other and are both highly involved in regulating how the other functions.

He will look at how inflammation in the brain can lead to the onset of a range of psychiatric symptoms including depression and anxiety related behaviours, and poor cognition which can potentially push an individual into developing a chronic psychiatric illness.

One of his key projects will look at identifying novel treatments for inflammation induced depression. “Current treatments for depression are ineffective for some people,” says Dr Walker.

“We know that in numerous studies, anti-inflammatories are playing a role to reduce symptoms of depression in patients.

“We’re looking at ways to target the blood-brain barrier and develop a novel antidepressant.”

In a research partnership with Professor Cyndi Shannon Weickert at NeuRA, Dr Walker will investigate the cause of the neuro inflammation in some people with schizophrenia.

“Clearly the brain and the immune system are talking to each other in this case, but the cause is unknown. This is an interesting opportunity to look at how the brain and the immune system communicate with each other and to hopefully help some people through our research,” says Dr Walker.

To find out more about Dr Walker’s research projects including depression and mood changes associated with cancer, please visit his research page at www.neura.edu.au/staff/dr-adam-walker

See what’s going on at NeuRA

FEEL THE BUZZ IN THE AIR? US TOO.