Blood pressure, retinal microvascular abnormalities, and dementia: considering the socioeconomic position

High blood pressure is related to the development of cerebral small vessel disease, retinal microvascular abnormalities, eye diseases (e.g. cataract and glaucoma), reduced visual acuity, and dementia. Cerebral small vessel disease, retinal microvascular abnormalities, eye diseases and vision are also related to the risk of dementia. Moreover, socioeconomic inequalities are related to blood pressure and dementia and may consequently shape the associations between blood pressure and risk of cerebral small vessel disease, retinal microvascular abnormalities, eye diseases and dementia. 

To date, there is no study investigating the indirect effects of cerebral small vessel disease, retinal microvascular abnormalities, eye diseases and vision impairment on dementia or cognitive decline and no study evaluating the influence of different socioeconomic indicators on these associations.