The prevalence of sleep apnoea in people with chronic quadriplegia is two to seven times higher than the general population. The causes likely differ compared to the abled body population. Thus, optimal treatment approaches may also differ. We are conducting an NHMRC-funded project to identify the causes of sleep apnoea in people with spinal cord injury and are running a clinical trial to test the effectiveness of a novel therapeutic intervention for people with spinal cord injury and sleep apnoea.