Imaging Genetics in Psychosis Study

This project established the cross-disorder cohort known as the Imaging Genetics in Psychosis Study, comprising more than 250 participants, including psychiatric patients diagnosed with schizophrenia, schizoaffective disorder, or bipolar disorder. In this study we consider the emerging genetic commonalities of these conditions in the context of parallel evidence for shared cognitive impairments characterized by poor prefrontal executive (working memory) and hippocampal (memory) function, and aberrant social cognitive (e.g., emotion processing) functions. Participants were recruited from 2009 through to 2015; each was interviewed about their current symptom levels and life experiences, completed a battery of cognitive tests, underwent structural, functional, and magnetic resonance brain scans, and gave blood and saliva for genetic and stress marker assays.

This project has received funding from the Australian Research Council (Future Fellowship; FT0991511), and the National Health and Medical Research Council (Project APP630471; 2010-2016).

Current PhD students: Leah Girshkin, Jesseca Rowland.