MEMOIR – a clinical trial for Complex Regional Pain Syndrome

Complex Regional Pain Syndrome (CRPS) is a disabling pain disorder, affecting approximately 5,000 people in Australia annually. It is characterised by severe burning, stinging and stabbing pain. People with CRPS are unable to use their painful limb and their ability to work or participate in normal social activities is severely restricted. Currently, there are no effective treatments for CRPS.

The MEMOIR Trial is a Commonwealth Government-funded, randomised controlled trial testing two novel treatments for CRPS. MEMOIR will test whether a drug, memantine, and a rehabilitation program, Graded Motor Imagery (GMI), produce greater improvements in pain intensity and function than placebo and standard care for CRPS.

The MEMOIR trial will be delivered remotely, via Telehealth, allowing Australia-wide recruitment of participants. Recruitment for MEMOIR will begin in early 2021. If you are interested in being contacted once recruitment has begun, please enter your details below.

MEMOIR Investigators

MEMOIR consolidates the expertise of scientists and clinicians:

  • A/Prof James McAuley, School of Medical Sciences & NeuRA, University of New South Wales
  • A/Prof Sylvia Gustin, School of Psychology & NeuRA, University of New South Wales
  • Prof Andrew McLachlan, Dean of Pharmacy, University of Sydney
  • Prof Lorimer Moseley, University of South Australia
  • Prof Benedict Wand, School of Physiotherapy, University of Notre Dame Australia
  • Dr Neil O’Connell, Brunel University London
  • Dr Hopin Lee, University of Oxford
  • Prof Eric Visser, School of Medicine, University of Notre Dame Australia
  • Prof Sallie Lamb, University of Exeter
  • Mr Michael Ferraro, NeuRA, University of New South Wales


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