Digitally created image of brain in skull

ForeFront

RESEARCH CENTRE

FTD and MND research group

ForeFront is a collaborative research group in Australia dedicated to the study of frontotemporal dementia (FTD) and motor neurone disease (MND).

FTD and MND are a group of disorders identified by distinct clinical signs and symptoms, and/or specific brain pathologies. These disorders are generally rapidly progressing, cause behavioural, language or motor deficits (often in combination), and together are a leading cause of dementia, particularly in people under 65 years of age.

ForeFront is an amalgamate of two government funded research groups:

Frontotemporal dementia and motor neurodegenerative syndromes
This National Health and Medical Research Council (NHMRC) program brings together a team of internationally recognised leaders in clinical, pathological and biological research on FTD and motor neurodegenerative syndromes. Individually these team leaders, along with their research staff, have made significant advances in these diseases, and this program will unify their efforts and focus on translating findings into better clinical information and intervention studies.

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Memory node of the ARC Centre of Excellence in Cognition and its Disorders This program investigates the cognitive systems and brain structures underlying various forms of memory, including autobiographical memory, episodic memory and semantic memory. The program uses experimental neuropsychological methods, as well as structural and functional brain imaging in patients with progressive brain pathologies such as frontotemporal dementia. Despite sustained research interest spanning 50 years, the cognitive and neural architecture of episodic and semantic memory systems and the factors that affect their optimal functions are still not fully understood.

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ReacStep – novel balance training programs to prevent falls in older adults

The ReacStep study is investigating the short-term effects of two balance training programs (i.e. reactive balance training and conventional balance training) on balance recovery from slips and trips in older adults. These programs are designed from evidence-based research and offer a challenging and unique experience to improving balance. The ReacStep team are calling on volunteers who: are aged 65 and over living independently in the Sydney metropolitan community can walk 500m comfortably with mobility aids or rest have not been advised by a medical practitioner not to exercise have no neurological conditions (e.g. Parkinson’s Disease, multiple sclerosis, Alzheimer’s, dementia, etc.) have no history or lower limb, pelvic or vertebral fracture(s) and/or lower limb joint replacement(s) in the past 6 months have no other existing conditions that may prevent them from exercising (e.g. injury, pain, fatigue, etc.) Eligible volunteers will be subjected to a health and safety screening before they are enrolled and randomly allocated into one of the two groups. Both groups will undertake a 3-week training program with an exercise physiologist, at NeuRA (i.e. in Randwick) as well as a balance recovery assessment at the 4-week time point. Reactive balance training involves intentionally stepping on a sliding tile, stepping over obstacles, trigger-release recovery as well as strength training. Participants will be wearing a full-body safety harness to ensure safety. Conventional balance training involves keeping balance in varying foot positions (i.e. feet together, in tandem or on one leg) whilst performing secondary tasks such as throwing a ball, card sorting, solving a maze or playing computer games. For more detailed information, read the Participant Information Statement and watch the video below. To get involved or to register your interest, click HERE. For all other queries, please contact the ReacStep Team on 02 9399 1002 or reacstep-study@neura.edu.au. HC210350 https://www.youtube.com/watch?v=ym0zlwqhXmw
PROJECT