The Motor Neurone Disease Behaviour Scale (MiND-B) is a valid, sensitive and short instrument that detects and quantifies behavioural changes in Amyotrophic Lateral Sclerosis (ALS). It measures three behavioural domains: apathy, disinhibition and stereotypical behaviour. The questionnaire contains 9 questions with a total score of 36, which higher scores denoting absence or very mild behavioural symptoms. The MiND-B can be completed by a caregiver/family member or clinician.
The MiND instrument and scoring guide can be downloaded below:
Wear, H.J., et al., The Cambridge Behavioural Inventory revised. Dementia & Neuropsychologia, 2008. 2(2): p. 102-107.
Neumann, M., et al., Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Science, 2006. 314(5796): p. 130-3.
Lillo, P., et al., Amyotrophic lateral sclerosis and frontotemporal dementia: A behavioural and cognitive continuum. Amyotrophic Lateral Sclerosis, 2012. 13(1): p. 102-9.
Lillo, P., et al., Grey and white matter changes across the amyotrophic lateral sclerosis-frontotemporal dementia continuum. PLoS ONE, 2012. 7(8): p. e43993.
Stewart, H., et al., Clinical and pathological features of amyotrophic lateral sclerosis caused by mutation in the C9ORF72 gene on chromosome 9p. Acta Neuropathologica, 2012. 123(3): p. 409-17.
Mioshi, E., et al., Neuropsychiatric changes precede classic motor symptoms in ALS and do not affect survival. Neurology, 2014. 82(2): p. 149-55.
Mioshi, E., et al., A novel tool to detect behavioural symptoms in ALS. Amyotroph Lateral Scler Frontotemporal Degener, 2014. 15(3-4): p. 298-304.
Hsieh, S., et al., The Mini-Addenbrooke’s Cognitive Examination: A new assessment tool for dementia. Dementia and Geriatric Cognitive Disorders, 2014. 39(1-2): p. 1-11.
In trying to understand the yet unknown causes about why older people fall over, we looked at fatigue. It is an ideal candidate. Firstly, fatigue is a common complaint for older people; more than 50 percent of people aged 70+ report fatigue in their daily activities. Secondly, fatigue affects sensory and movement functions that are associated with falling, such as […]