Our response to COVID-19

We're supporting people to maintain their wellbeing and manage isolation.

Digitally created image of brain in skull

ForeFront

RESEARCH CENTRE

Students

The program aims to provide rigour and excellence in laboratory and clinical research training to the next generation of clinical researchers.

From the laboratory perspective, we will continue to train PhD and honours students through university academic programs, and to mentor postdoctoral researchers to develop into independent scientists. We will disseminate the wide range of experimental techniques and model systems that are used in this program to train the next generation of molecular neuroscientists.

From the clinical perspective, we propose to expand the current personnel by supporting clinical fellows, provide for PhD scholarship stipends, in addition to funding a dedicated clinical research neuropsychologist, occupational therapist, speech pathologist, clinical nurse specialist, exercise physiologist and database manager. As such, the program will train clinical researchers and will facilitate development of career paths that encompass integrated neuroscience and clinical skills. This strategy will ensure an emerging cohort of clinician researchers who can facilitate translation of neuroscience findings into clinical practice and, importantly, optimise public health benefits by disseminating most recent evidence-based practice to community settings. Each clinician researcher will be trained in an interdisciplinary culture, co-supervised by investigators with different areas of expertise, thereby promoting integration of diverse approaches.

Prof Kril has academic expertise in research student training (Assoc Dean, Postgraduate Studies, Sydney Medical School) and will take prime responsibility for developing and overseeing training and mentoring within the program with the remit to substantially grow our capacity in this area.

For more information on how to get involved with either the clinical or laboratory based research please contact jillian.kril@sydney.edu.au.

See what’s going on at NeuRA

FEEL THE BUZZ IN THE AIR? US TOO.

What is the analgesic effect of EEG neurofeedback for people with chronic pain? A systematic review

Researchers: A/Prof Sylvia Gustin, Dr Negin Hesam-Shariati, Dr Wei-Ju Chang, A/Prof James McAuley, Dr Andrew Booth, A/Prof Toby Newton-John, Prof Chin-Teng Lin, A/Prof Zina Trost Chronic pain is a global health problem, affecting around one in five individuals in the general population. The understanding of the key role of functional brain alterations in the generation of chronic pain has led researchers to focus on pain treatments that target brain activity. Electroencephalographic (EEG) neurofeedback attempts to modulate the power of maladaptive EEG frequency powers to decrease chronic pain. Although several studies provide promising evidence, the effect of EEG neurofeedback on chronic pain is uncertain. This systematic review aims to synthesise the evidence from randomised controlled trials (RCTs) to evaluate the analgesic effect of EEG neurofeedback. The search strategy will be performed on five electronic databases (Cochrane Central, MEDLINE, Embase, PsycInfo, and CINAHL) for published studies and on clinical trial registries for completed unpublished studies. We will include studies that used EEG neurofeedback as an intervention for people with chronic pain. Risk of bias tools will be used to assess methodological quality of the included studies. RCTs will be included if they have compared EEG neurofeedback with any other intervention or placebo control. The data from RCTs will be aggregated to perform a meta-analysis for quantitative synthesis. In addition, non-randomised studies will be included for a narrative synthesis. The data from non-randomised studies will be extracted and summarised in a descriptive table. The primary outcome measure is pain intensity assessed by self-report scales. Secondary outcome measures include depressive symptoms, anxiety symptoms, and sleep quality measured by self-reported questionnaires. Further, we will investigate the non-randomised studies for additional outcomes addressing safety, feasibility, and resting-state EEG analysis.
PROJECT