Centre for Pain IMPACT

RESEARCH CENTRE

INVESTIGATING MECHANISMS OF PAIN TO ADVANCE CLINICAL TRANSLATION

The Centre for Pain IMPACT, directed by Prof James McAuleyA/Prof Sylvia Gustin, Dr Siobhan Schabrun and A/Prof David Seminowicz conducts research that encompasses basic science through to clinical and translational research.

Our research investigates the causes of chronic pain; develops and tests the efficacy and effectiveness of new treatment approaches; and implements new treatment approaches into clinical practice.

The research covers a range of conditions: low back pain, osteoarthritis, temporomandibular disorder, focal hand dystonia, headache, complex regional pain syndrome, migraine, burning mouth syndrome, sickle cell disease, fibromyalgia, rheumatoid arthritis, spinal cord injury neuropathic pain, trigeminal neuropathic pain and trigeminal neuralgia.

Our team uses different research methods, including animal (rodent) models, human models, neuroimaging, experimental methods (non-invasive brain stimulation, quantitative sensory testing), cohort studies, randomised controlled trials, implementation trials, and qualitative research.

The Centre also provides ongoing pain-related educational activities, including media, public lectures, clinical workshops, and seminars.

The overarching aims of the Centre for IMPACT are to:

  • profile NeuRA’s world class pain research
  • facilitate collaboration within and beyond NeuRA
  • raise awareness of NeuRA’s pain activities by providing:
    • a platform for research participant recruitment
    • a forum for public and clinician education
    • leverage expertise within NeuRA to seek external funding support (e.g. NHMRC CRE, industry, philanthropy).

LATEST NEWS AND EVENTS

Back and Neck Pain Forum

Please follow this link to the Back & Neck Pain Forum official webpage!

 

 


CENTRE FOR PAIN IMPACT TEAM

THIAGO FOLLY Research Assistant

NELL NORMAN-NOTT PhD Student

BROOKE NAYLOR Masters Student, Clinical Psychology

DANIEL HULTBERG Medical Student

ANTON PAULSON Medical Student

DAVID KANG Medical Student

PAULINE ZAHARA Clinical Trial Manager

YANNICK GILANYI Research Associate : y.gilanyi@neura.edu.au

BRISHNA SHAH Research Associate : b.shah@neura.edu.au

JACK DEVONSHIRE Honours Student : j.devonshire@neura.edu.au

HARRISON HANSFORD Honours Student : h.hansford@neura.edu.au

ANIKA HAIGH Research Assistant : a.haigh@neura.edu.au

DR IAN SKINNER Postdoctoral Research Fellow

LUKE JENKINS PhD Student

REBECCA LIVINGS PhD Student

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Brain and Knee Muscle Weakness Study

Why Does Quadriceps Weakness Persist after Total Knee Replacement? An Exploration of Neurophysiological Mechanisms Total knee replacement is a commonly performed surgery for treating end-staged knee osteoarthritis. Although most people recover well after surgery, weakness of the quadriceps muscles (the front thigh muscles) persists long after the surgery (at least for 12 months), despite intensive physiotherapy and exercise. Quadriceps muscle weakness is known to be associated with more severe pain and greatly affect daily activities. This study aims to investigate the mechanisms underlying weakness of the quadriceps muscles in people with knee osteoarthritis and total knee replacement. We hope to better understand the relationship between the changes of the brain and a loss of quadriceps muscle strength after total knee replacement. The study might be a good fit for you if you: Scheduled to undergo a total knee replacement; The surgery is scheduled within the next 4 weeks; Do not have a previous knee joint replacement in the same knee; Do not have high tibial osteotomy; Do not have neurological disorders, epilepsy, psychiatric conditions, other chronic pain conditions; Do not have metal implants in the skull; Do not have a loss of sensation in the limbs. If you decide to take part you would: Be contacted by the researcher to determine your eligibility for the study Be scheduled for testing if you are eligible and willing to take part in the study Sign the Consent Form when you attend the first testing session Attend 3 testing sessions (approximately 2 hours per session): 1) before total knee replacement, 2) 3 months and 3) 6 months after total knee replacement. The testing will include several non-invasive measures of brain representations of the quadriceps muscles, central pain mechanisms, and motor function and questionnaires. Will I be paid to take part in the research study? You will be reimbursed ($50.00 per session) for travel and parking expenses associated with the research study visits. If you would like more information or are interested in being part of the study, please contact: Name: Dr Wei-Ju Chang Email: w.chang@neura.edu.au Phone: 02 9399 1260 This research is being funded by the Physiotherapy Research Foundation.  
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