Portrait of Prof Olivier Piguet



FRONTIER investigates the neurological, psychological and biological basis of brain function in frontotemporal dementia (FTD) and healthy ageing.


FRONTIER Family & Support Person Information Day: 11am-4pm Friday June 10th 2016

This day is open to any family member or carer of a person with Frontotemporal Dementia. To RSVP please email name, contact details and number attending to: s.homewood@neura.edu.au. See program here

2018 ISFTD International Conference awarded to Sydney

The bid led by A/Prof Olivier Piguet to host the 2018 International Conference on frontotemporal dementias in Sydney was successful. More information will following in the coming weeks.

FRONTIER 2015 Newsletter
Read here all the updates and news that has happened through the year here.

FRONTIER Executive Screen (FES)
The FES (a short bedside screening instrument to test the integrity of executive function) is now available.

Muireann Irish awarded L’Oreal Women in Science Fellowship – 9 August 2015
Dr Muireann Irish was awarded a L’Oreal-UNESCO Australia & New Zealand for Women in Science Fellowship. Muireann was selected from over 400 candidates. This prestigious fellowship is in recognition for her work on memory and dementia.More information can be found here:http://loreal.scienceinpublic.com.auand a short video of Muireann speaking about her work is at: http://loreal.scienceinpublic.com.au/memory

Prof John Hodges receives life achievement award – 19 July 2015

Professor John Hodges was awarded the Bengt Winblad Lifetime Achievement Award in Alzheimer’s Disease Research for his work in cognition in neurodegenerative conditions. He was presented the award at the opening session at the Alzheimer’s Association Conference in Washington DC, USA. Media release

Available now – Revised Younger Onset Dementia (YOD) booklet produced by Alzheimer’s Australia and FRONTIER.

Phd Project Opportunities details here

FRONTIER Communications
Listen to Professor Hodges (Ep1 and 2) and Associate Professor Olivier Piguet (Ep 10) discussing dementia, corticobasal syndrome and the ACE Mobile

Carers, patients & volunteers
One of the aims of FRONTIER is to provide information and support for patients, carers and their families.

More about Carers
FRONTIER Publications
Ahmed, R.M., Irish, M., Henning, E., Dermody, N., Bartley, L., Kiernan, M.C., Piguet, O., Farooqi, S., Hodges, J.R. (in press) Assessment of Eating Behavior Disturbance and Associated Neural Networks in Frontotemporal Dementia. JAMA Neurology, Jan 25. [Epub ahead of print]
Kumfor, F., Landin-Romero, R., Devenney, E., Hutchings, R., Grasso, R., Hodges, J.R., Piguet O. (2016) On the right side? A longitudinal study of left- vs. rightl-ateralised semantic dementia. Brain, 139(Pt 3), 986-998.
Leyton, C., Britton, A.K., Hodges, J.R., Halliday, G.M., Kril, J.J. (2016) Distinctive pathological mechanism involved in primary progressive aphasias. Neurobiology of Aging, 38, 82-92.
Wong, S., Bertoux, M., Savage, G., Hodges, J.R., Piguet, O., Hornberger, M. (in press) Comparison of prefrontal atrophy and episodic memory performance in dysexecutive Alzheimer’s disease and behavioural-variant frontotemporal dementia. Journal of Alzheimer’s Disease, Feb 25. [Epub ahead of print]
For other publications click here
FRONTIER Resources
Younger Onset Dementia (YOD) impacts on thousands of Australians – from the immediate family and friends to those in the community who, often by chance, have to cope with YOD sufferers.

Younger Onset Dementia can begin to affect people in their 40’s – in the prime of their lives.

The five-chapter, 38 page online booklet produced by the Neuroscience Research Australia (formerly Prince of Wales Medical Research Institute (POWMRI), is based on 20 years of research and is designed to help those living with or exposed to people showing early onset dementia signs as well as those confirmed to already have symptoms. Download the guide here.

Test downloads
FRONTIER has developed 8 clinical assessments which are freely available. More information and instructions are available here.
New ACE mobile available now. Download here.
Related Downloads
2016 FTD Information Day Flyer (PDF)

See what’s going on at NeuRA


'I've got the best job for you dad. Your shaky arm will be perfect for it!'

Children… honest and insightful. Their innocence warms the heart. But what words do you use to explain to a child that daddy has an incurable brain disease? What words tell them that in time he may not be able to play football in the park, let alone feed himself? What words help them understand that in the later stages, dementia may also strike? Aged just 36, this was the reality that faced Steve Hartley. Parkinson's disease didn't care he was a fit, healthy, a young dad and devoted husband. It also didn't seem to care his family had no history of it. The key to defeating Parkinson's disease is early intervention, and thanks to a global research team, led by NeuRA, we're pleased to announce that early intervention may be possible. Your support, alongside national and international foundations Shake it Up Australia and the Michael J Fox Foundation, researchers have discovered that a special protein, found in people with a family history of the disease increases prior to Parkinson’s symptoms developing. This is an incredible step forward, because it means that drug therapies, aimed at blocking the increase in the protein, can be administered much earlier – even before symptoms strike. The next step is to understand when to give the drug therapies and which people will most benefit from it. But we need your help. A gift today will support vital research and in time help medical professionals around the world treat Parkinson’s disease sooner, with much better health outcomes. Thank you, in advance, for your support.  


Physiological factors associated with falls in an elderly population.

Lord SR, Clark RD, Webster IW

To determine whether a battery of 13 sensorimotor, vestibular, and visual tests discriminates between elderly fallers and elderly non-fallers. It appears that this approach highlights some key physiological factors that predispose elderly individuals to falls.