Digitally created image of a double helix

Genetic Repositories Australia (GRA)

FACILITY INFORMATION

What is Genetic Repositories Australia (GRA)?

GRA provides Australian medical researchers with a national facility for the processing, long-term secure storage and distribution to qualified investigators of human genetic material (DNA and cell lines) collected from patients and healthy participants from studies on a range of diseases and their outcomes to facilitate genetic analyses for medical research.

Who will use GRA & why consider submitting samples?

Submission of samples (blood/tissue etc) to the Repository may give scientists material that can help them to develop new understanding about the cause of disease, new diagnostic tests, new treatments, and new ways to prevent diseases.

Where is GRA located?

GRA is located at Neuroscience Research Australia, Randwick, NSW, Sydney, Australia.

What happens to the blood/saliva/tissue sample?

Samples are sent to the GRA facility where genetic material (DNA) will be extracted from the sample. In order to ensure an ongoing source of DNA, white blood cells (lymphocytes) are cultured and kept growing in the laboratory, as a cell line, which allows a source of genetic material without having to obtain another blood sample. These cell lines can be stored indefinitely.

What happens to samples if GRA closes?

The genetic material stored by GRA is a precious and scientifically valuable resource that should not be lost to future medical research, however in the event GRA closes, attempts will be made initially to transfer samples to a third party willing to undertake the responsibility for managing GRA. This would only occur if the third party adhered to the current guidelines set out by the GRA Scientific Advisory Committee and the National Statement on Ethical Conduct in Human Research (2007). Should no third party exist, or if funding for this initiative ceased, then GRA will no longer operate and all genetic samples and accompanying data will be destroyed.

Will GRA provide any results to participants?

Since the results generated from samples are for research purposes only, no results will be provided to participants. However, in the event that information of clinical significance (i.e. one which has a significant probability of impacting on the health of the participant or that of the participant’s children) is identified by the researchers using samples sourced from GRA, every effort will be made to contact the participant through the Chief investigator of the recruiting study.

What happens if a participant decides to withdraw samples from the GRA repository collection?

Donation is entirely voluntary and if a participant chooses to withdraw, there will be no penalty or loss of benefits. If the participant wishes to withdraw samples from GRA, this can be done by notifying the Chief Investigator of the recruiting study. If the participant withdraws from the study, GRA will follow the directions of the relevant Chief Investigator to destroy the participant sample or to allow the participant sample to continue to be used.

What are the benefits of participating in GRA’s repository collection?

You will not directly benefit from the research conducted using your genetic material, nor will you receive either now or in the future any payment, compensation, royalty or any other financial benefit which may result from the research, but your sample may benefit the community at large or some particular group. We thank you for your participation – your assistance will help advance medical research.

If I have any questions who should I contact?

Further information is available by contacting +61 2 9399 1746 or gra.notify@neura.edu.au

See what’s going on at NeuRA

FEEL THE BUZZ IN THE AIR? US TOO.

MyCOACH: Connected Advice for Cognitive Health

Researchers at Neuroscience Research Australia (NeuRA) and University of New South Wales (UNSW) are inviting people with Mild Cognitive Impairment (MCI) or Subjective Cognitive Decline (SCD) to participate in a voluntary online research trial aiming to reduce the risk of dementia. What is the MyCOACH Trial about? This research aims to test the effectiveness of an e-learning and behaviour change course designed to support healthy brain ageing and reduce risk of dementia.  The course is tailored for people reporting cognitive difficulties or changes. The trial runs for 12 weeks, with a follow up at 1 and 2 years afterwards. What is involved in this research trial? Interested volunteers will be asked to complete some eligibility checks to confirm this study is a good match.    If you decide to take part you would: Be placed into either the MyCOACH e-learning group (“Intervention”) or the Control Education group (“Control”). To ensure the research is fair and unbiased, we cannot choose the group for you.   It will be random - like names out of a hat. MyCOACH e-learning group (“Intervention”):  Volunteers in this group participate in the 12 week online MyCOACH program.  This includes 6 e-learning chapters, as well as three phone consultations with a dietician and/or exercise physiologist, and a 3-month subscription to a brain training app. Control Education group (“Control”): Volunteers in this group will receive information about cognitive health and risk factors for dementia.  This group is important to be able to measure the effectiveness of the research.  At the end of the study, volunteers in this “control” group can access the full MyCOACH e-learning course. Take part in four telephone interviews throughout the study with questions about your health. This includes a follow-up at the end of 12 weeks, and 1 and 2 years later. You may be eligible to participate in the MyCOACH Trial if you: Have concerns about changes in your memory or thinking OR diagnosed with ‘Mild Cognitive Impairment’ Are 65 years of age or older   Expressions of interest [ninja_forms id=376]   Contact If you are interested or know someone who might be, please contact us for more information: Dinaz Parekh Email: mycoach@neura.edu.au Phone: (02) 9399 1815
PROJECT