Digitally created image of a double helix

Genetic Repositories Australia (GRA)

FACILITY INFORMATION

Scientists around the world will soon be embarking on a race to discover the secrets of longevity by mapping the genome of 100 people aged over 100. This global, incentivized competition known as the Archon Genomics X PRIZE offers a $10 million prize awarded to the first team to rapidly, accurately and economically sequence 100 whole human genomes to an unprecedented level of accuracy. The GRA facility has been producing cell lines for the Sydney Centenarian Study and will be providing up to 15 Australian Centenarian samples to accompany others from around the world to hopefully provide researchers valuable clues to health and longevity. The ABC 730 Report talks more:

http://www.abc.net.au/7.30/content/2012/s3479716.htm

New project additions have also seen the GRA facility supporting studies investigating the genomics of cerebral palsy, gene mutations for motor neuron disease and more recently stroke. We also continue to process samples for an international collaborative project investigating dominantly inherited Alzheimer’s disease (DIAN). NeuRA forms one of ten study sites in the US, UK and Australia that make up the DIAN Network. The DIAN Network utilises the GRA facility as the sole service provider for Australia. We are producing cell lines that are subsequently deposited into the National Cell Repository for Alzheimer’s disease (NCRAD) at the University of Illinois in the US.

Previously GRA became the first facility in Australia to acquire a fully automated high volume nucleic acid purification system (QIAGEN Autopure LS). With conventional manual DNA extraction methods both time and labour intensive, its acquisition has allowed GRA to be at the forefront in the provision of high volume DNA extraction services and has since increased GRA productivity and research efficiency resulting in consistent high quality DNA purification. DNA sample type extraction services have been expanded through the ability to fully automate processing of DNA from blood, saliva (Oragene®), cell lysates and transformed cell lines. GRA accepted delivery and installation of the unit in May 2008, over 10000 samples have already been processed.

A significant number of NHMRC and ARC funded research projects throughout Australia have already been supported by GRA’s enhanced research capacities by use of the Autopure unit being able to provide high quality, high molecular weight DNA samples suitable for archiving and excellent performance on sensitive downstream applications.

See what’s going on at NeuRA

FEEL THE BUZZ IN THE AIR? US TOO.

MyCOACH: Connected Advice for Cognitive Health

Researchers at Neuroscience Research Australia (NeuRA) and University of New South Wales (UNSW) are inviting people with Mild Cognitive Impairment (MCI) or Subjective Cognitive Decline (SCD) to participate in a voluntary online research trial aiming to reduce the risk of dementia. What is the MyCOACH Trial about? This research aims to test the effectiveness of an e-learning and behaviour change course designed to support healthy brain ageing and reduce risk of dementia.  The course is tailored for people reporting cognitive difficulties or changes. The trial runs for 12 weeks, with a follow up at 1 and 2 years afterwards. What is involved in this research trial? Interested volunteers will be asked to complete some eligibility checks to confirm this study is a good match.    If you decide to take part you would: Be placed into either the MyCOACH e-learning group (“Intervention”) or the Control Education group (“Control”). To ensure the research is fair and unbiased, we cannot choose the group for you.   It will be random - like names out of a hat. MyCOACH e-learning group (“Intervention”):  Volunteers in this group participate in the 12 week online MyCOACH program.  This includes 6 e-learning chapters, as well as three phone consultations with a dietician and/or exercise physiologist, and a 3-month subscription to a brain training app. Control Education group (“Control”): Volunteers in this group will receive information about cognitive health and risk factors for dementia.  This group is important to be able to measure the effectiveness of the research.  At the end of the study, volunteers in this “control” group can access the full MyCOACH e-learning course. Take part in four telephone interviews throughout the study with questions about your health. This includes a follow-up at the end of 12 weeks, and 1 and 2 years later. You may be eligible to participate in the MyCOACH Trial if you: Have concerns about changes in your memory or thinking OR diagnosed with ‘Mild Cognitive Impairment’ Are 65 years of age or older   Expressions of interest [ninja_forms id=376]   Contact If you are interested or know someone who might be, please contact us for more information: Dinaz Parekh Email: mycoach@neura.edu.au Phone: (02) 9399 1815
PROJECT