NeuRA Imaging Centre


Identifying fMRI Model Violations with Lagrange Multiplier Tests (Ben Cassidy)

This software comprises tools for identifying model violation in Functional Magnetic Resonance Imaging analysis. The diagnostic tests are available as a MATLAB toolbox, and can be run from the MATLAB command line or incorporated in batch scripts as part of a full fMRI analysis pipeline.

The current version includes tests for violation of the following model assumptions:
– Double Gamma (canonical) hemodynamic response function
– Double Gamma and temporal derivative HRF (derivative as defined in SPM software)
– Double Gamma and temporal derivative HRF (derivative as defined in FSL software)
– Time-varying HRF
– Non-linear HRF

Download software (version 0.3)
Latest software version and development branches available at

Cassidy, B., Long, C.J., Rae, C and Solo, V.
Identifying fMRI model violations with Lagrange multiplier tests.
IEEE Transactions in Medical Imaging (in press 03/04/2012).

Cassidy, B and Solo, V.
fMRI Model Diagnostics for the Double Gamma and Temporal Derivative,
IEEE International Symposium on Biomedical Imaging, 2012

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