Dr Claire Shepherd in Brain Bank lab

Sydney Brain Bank

FACILITY INFORMATION

Neurodegenerative disorders, such as Alzheimer’s and Parkinson’s disease, have a huge personal impact in addition to being an increasing economic burden to individuals and the community. There are currently no treatments for many of these disorders, and only symptomatic treatment for some.

Current imaging techniques still cannot assess many cellular biological aspects of the brain, particularly at the molecular level. This is the level that is primarily affected in neurodegenerative diseases, and is the level required to definitively diagnose these diseases and to understand their cellular causes. This is why such tissue is needed for research into understanding and curing these disorders.

 

According to the Australian Government, Department of Health and Ageing;
• In 2011, it was estimated that 298,000 individuals were living with dementia in Australia
• Those aged 65 years or older, almost 1 in 10 had dementia
• This increased to 3 in 10 who had dementia for those aged 85 years or older.
• With the increase of Australia’s elderly population, dementia cases are expected to triple by 2050.
• In 2010 dementia was one of the leading causes of death behind cerebrovascular diseases and ischaemic heart diseases.

Researchers in Australia and overseas interested in investigating areas such as basic disease mechanisms, earlier and more accurate diagnosis, genetic contributions to diseases, better treatments, and ultimately, cure and prevention, can request this tissue for their research studies.

To be successful in our goals, we rely on the generosity and altruism of people who donate their brains for research and also the scientists who request the tissue seeking to alleviate the suffering that neurodegenerative diseases cause.

See what’s going on at NeuRA

FEEL THE BUZZ IN THE AIR? US TOO.

The cold case of schizophrenia - broken wide open!

‘It is like they were miraculously healed!’’ Schizophrenia is diagnosed by clinical observation of behaviour and speech. This is why NeuRA researchers are working hard to understand the biological basis of the illness. Through hours of work and in collaboration with doctors and scientists here and around the world, NeuRA has made an amazing breakthrough. For the first time, researchers have discovered the presence of antibodies in the brains of people who lived with schizophrenia. Having found these antibodies, it has led NeuRA researchers to ask two questions. What are they doing there? What should we do about the antibodies– help or remove them? This is a key breakthrough. Imagine if we are treating schizophrenia all wrong! It is early days, but can you imagine the treatment implications if we’ve identified a new biological basis for the disease? It could completely change the way schizophrenia is managed, creating new treatments that will protect the brain. More than this, could we be on the verge of discovering a ‘curable’ form of schizophrenia? How you can help We are so grateful for your loyal support of schizophrenia research in Australia, and today I ask if you will consider a gift today. Or, to provide greater confidence, consider becoming a Discovery Partner by making a monthly commitment. We believe there is great potential to explore these findings. Will you help move today’s breakthrough into tomorrow’s cure? To read more about this breakthrough, click ‘read the full story’ below. You are also invited to read ‘Beth’s story’, whose sweet son Marcus lived with schizophrenia, by clicking here.
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