Brain tissue arrives at the Sydney Brain Bank from around Australia and is processed and stored in different ways as a means of offering the greatest options for researchers who may want to utilise the tissues for their experiments.
Specifically, some of the tissue is frozen so that it can be used for DNA extraction or biochemical studies. This is done in the shortest time period possible to ensure viability of most neurochemicals, protein and RNA.
For participants with a strong family history of disease, the DNA may be screened for genes in which rare mutations have already been associated with neurodegeneration. The remaining tissue is fixed in formalin to preserve it for histological examination.
12. Associate Professor Tony Roscioli Elusive genes could reassure parents of cleft lip and palate babies Sydney Morning Herald Cleft lip and palate are some of the most common birth defects globally, affecting one in 800 children. Roughly 250 Australian children are born with the conditions each year. A team of Australian and international scientists led by NeuRA’s Associate Professor […]