The brain donation occurs as soon as possible after death. This is done with the utmost care and respect by highly trained staff who perform the brain removals. The limited autopsies are usually carried out at the nearest participating hospital that has appropriate mortuary facilities. After the procedure, the tissue is transported back to the Sydney Brain Bank where it is processed and held.
The tissue is processed and stored in different ways as a means of offering the greatest options for researchers who may want to utilise the tissues for their experiments. This may include freezing some of the tissue so that it can be used for DNA extraction and/or biochemical studies. The remaining tissue is fixed in formalin to preserve it for histological examination.
A new study by Prof Rob Herbert and his team is investigating muscle contracture in children with cerebral palsy. Contracture is a stiffening of muscles, even when the muscle is passive. It is not yet known whether contracture is a result of changes in the muscle, changes in the associated tendon, or a combination of both. Around 53 per cent […]