Senior Postdoctoral Research Fellow
Dr Aidan Cashin is a NHMRC Emerging Leadership Fellow at Neuroscience Research Australia (NeuRA) and an associate lecturer in the School of Health Sciences at the University of New South Wales. A member of the Centre for Pain IMPACT, his PhD focused on improving the evidence-based management of low back pain. Aidan was awarded the 2022 Ronald Dubner Research Prize by the International Association for the Study of Pain (IASP) for the best doctoral thesis in the field of pain. Prior to commencing research, Aidan pursued a successful clinical career as an Accredited Exercise Physiologist, practicing primarily in the field of chronic musculoskeletal pain.
Aidan’s current research deals with investigating the mechanisms of healthcare interventions for optimization and translation into clinical practice and health policy. Most of Aidan’s work is applied to the management of chronic musculoskeletal pain conditions, and he also conducts methodological work that aims to improve research transparency and openness. Follow Aidan’s work on Google Scholar and ORCID.
To learn more about MEMOIR please visit our new website memoir.neura.edu.au
Medicines are the most common treatment for back pain. The aim of this program of research is to improve our understanding of the clinical effects of medicines.
Studies currently in progress:
Medicines for Back Pain – Publications:
Medicines for Back Pain – Registrations of Study Protocols:
There are a growing number of studies using mediation analysis to understand the mechanisms of health interventions and exposures. Recent work has shown that the reporting of these studies is heterogenous and incomplete. This problem stifles clinical application, reproducibility, and evidence synthesis. The development and implementation of A Guideline for Reporting Mediation Analyses (AGReMA) will improve the standardization, transparency, and completeness in the reporting of studies that use mediation analysis to understand the mechanisms of health interventions and exposures.
Cashin AG, McAuley JH, Lamb SE, Hopewell S, Kamper SJ, Williams CM, Henschke N, Lee H. (2020). Development of A Guideline for Reporting Mediation Analyses (AGReMA). BMC Med Res Methodol 20(1):19. doi: 10.1186/s12874-020-0915-5. PMID: 32013883
YANNICK GILANYI Honours Student : firstname.lastname@example.org
BRISHNA SHAH Honours Student : email@example.com
JACK DEVONSHIRE Research Assistant : firstname.lastname@example.org
HARRISON HANSFORD Doctoral Candidate : email@example.com
THIAGO FOLLY Research Assistant
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PAULINE ZAHARA Clinical Trial Manager
DR IAN SKINNER Postdoctoral Research Fellow
The objective of this study was to review and assess the methodological quality of randomized controlled trials that test physical therapy interventions for low back pain. Most trials that test physical therapy interventions for low back pain have methodological limitations that could bias treatment effect estimates. Greater attention to methodological features, such as allocation concealment and the reporting of intention-to-treat effects, would improve the quality of trials testing physical therapy interventions for low back pain.
Mediation analysis is a widely used quantitative method for investigating how interventions and exposures in randomised controlled trials and observational studies have an effect on healthcare outcomes. This study aimed to assess the importance of items that should be considered in a consensus meeting aimed at developing a guideline for reporting mediation analyses. This Delphi study used a rigorous consensus process to reach consensus on 34 reporting items for studies that use mediation analysis. These results will inform a consensus meeting that will consolidate a core set of recommended items for reporting mediation analyses.