Postdoctoral Research Fellow
02 9399 1870
Aidan Cashin is a Postdoctoral Research Fellow at Neuroscience Research Australia (NeuRA). A member of the Centre for Pain IMPACT, his research deals with investigating the mechanisms of treatments for musculoskeletal pain conditions including low back pain. He is also interested in increasing the openness and transparency of research and is involved in developing a reporting guideline for studies that use mediation analysis. Follow Aidan’s work on Google Scholar and ORCID.
Prior to commencing research, Aidan pursued a successful clinical career as an Accredited Exercise Physiologist, practicing primarily in the field of chronic musculoskeletal pain. Aidan also has an academic position at the University of New South Wales, within the School of Health Sciences and is involved in the teaching and evaluating of undergraduate exercise physiology students.
MEMOIR is an Australian government-funded clinical trial for Complex Regional Pain Syndrome (CRPS). MEMOIR is testing two treatments for people with CRPS – a drug, memantine and a rehabilitation program, Graded Motor Imagery. MEMOIR will be conducted remotely, via Telehealth, allowing for Australia-wide recruitment of eligible participants. Please click on the link below to check if you are eligible.
Medicines are the most common treatment for back pain. The aim of this program of research is to improve our understanding of the clinical effects of medicines.
Studies currently in progress:
Medicines for Back Pain – Publications:
Medicines for Back Pain – Registrations of Study Protocols:
There are a growing number of studies using mediation analysis to understand the mechanisms of health interventions and exposures. Recent work has shown that the reporting of these studies is heterogenous and incomplete. This problem stifles clinical application, reproducibility, and evidence synthesis. The development and implementation of A Guideline for Reporting Mediation Analyses (AGReMA) will improve the standardization, transparency, and completeness in the reporting of studies that use mediation analysis to understand the mechanisms of health interventions and exposures.
Cashin AG, McAuley JH, Lamb SE, Hopewell S, Kamper SJ, Williams CM, Henschke N, Lee H. (2020). Development of A Guideline for Reporting Mediation Analyses (AGReMA). BMC Med Res Methodol 20(1):19. doi: 10.1186/s12874-020-0915-5. PMID: 32013883
YANNICK GILANYI Research Associate : email@example.com
BRISHNA SHAH Research Associate : firstname.lastname@example.org
JACK DEVONSHIRE Honours Student : email@example.com
HARRISON HANSFORD Honours Student : firstname.lastname@example.org
THIAGO FOLLY Research Assistant
ANIKA HAIGH Research Assistant : email@example.com
PAULINE ZAHARA Research Assistant
DR IAN SKINNER Postdoctoral Research Fellow
The objective of this study was to review and assess the methodological quality of randomized controlled trials that test physical therapy interventions for low back pain. Most trials that test physical therapy interventions for low back pain have methodological limitations that could bias treatment effect estimates. Greater attention to methodological features, such as allocation concealment and the reporting of intention-to-treat effects, would improve the quality of trials testing physical therapy interventions for low back pain.
Mediation analysis is a widely used quantitative method for investigating how interventions and exposures in randomised controlled trials and observational studies have an effect on healthcare outcomes. This study aimed to assess the importance of items that should be considered in a consensus meeting aimed at developing a guideline for reporting mediation analyses. This Delphi study used a rigorous consensus process to reach consensus on 34 reporting items for studies that use mediation analysis. These results will inform a consensus meeting that will consolidate a core set of recommended items for reporting mediation analyses.