Bill Brooksprofile image
Dr

Bill Brooks


Current Appointments

Senior Research Fellow (Honorary)
Conjoint Senior Lecturer, Prince of Wales Clinical School, UNSW Honorary Visiting Medical Officer, Cognitive Disorders Clinic, Prince of Wales Hospital
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Dr Bill Brooks graduated in Medicine from the University of Sydney in 1978. Since 1988 he has been studying families with the inherited forms of Alzheimer’s disease and similar conditions including familial frontotemporal dementia, initially at Concord Hospital and the University of Sydney. He moved to the NeuRA campus in 2002. His work involves collaboration with the Schofield and Kwok groups for genetic studies and the Halliday group for neuropathological research, as well as the Frontier group for frontotemporal dementia research. Bill is currently working on the DIAN study (Dominantly Inherited Alzheimer Network), an international study of familial Alzheimer’s disease funded by the US National Institute on Ageing.


Publications

2022 Feb

Confirming Pathogenicity of the F386L PSEN1 Variant in a South Asian Family With Early-Onset Alzheimer Disease

View full journal-article on https://doi.org/10.1212/NXG.0000000000000647

2020

A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer’s disease

View full journal-article on http://www.scopus.com/inward/record.url?eid=2-s2.0-85081697081&partnerID=MN8TOARS

2020

Amyloid and Tau Pathology Associations With Personality Traits, Neuropsychiatric Symptoms, and Cognitive Lifestyle in the Preclinical Phases of Sporadic and Autosomal Dominant Alzheimer's Disease

View full journal-article on http://www.scopus.com/inward/record.url?eid=2-s2.0-85082547156&partnerID=MN8TOARS

2020

CYLD is a causative gene for frontotemporal dementia - amyotrophic lateral sclerosis

View full journal-article on http://www.scopus.com/inward/record.url?eid=2-s2.0-85082342425&partnerID=MN8TOARS

2019

An atlas of cortical circular RNA expression in Alzheimer disease brains demonstrates clinical and pathological associations

View full journal-article on http://www.scopus.com/inward/record.url?eid=2-s2.0-85074211513&partnerID=MN8TOARS

2019

Comparison of Pittsburgh compound B and florbetapir in cross-sectional and longitudinal studies

View full journal-article on http://www.scopus.com/inward/record.url?eid=2-s2.0-85061783606&partnerID=MN8TOARS

2019

Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia

View full journal-article on http://www.scopus.com/inward/record.url?eid=2-s2.0-85058010718&partnerID=MN8TOARS

2019

Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer’s disease

View full journal-article on http://www.scopus.com/inward/record.url?eid=2-s2.0-85060347238&partnerID=MN8TOARS

2018

A C6orf10/LOC101929163 locus is associated with age of onset in C9orf72 carriers

View full journal-article on http://www.scopus.com/inward/record.url?eid=2-s2.0-85054408708&partnerID=MN8TOARS

2018

Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies

View full journal-article on http://www.scopus.com/inward/record.url?eid=2-s2.0-85041689945&partnerID=MN8TOARS