Dr Karen Mather

TEAM LEADER PROFILE

Senior Research Scientist Leader of the Genetics and Epigenomics Group, Centre for Healthy Brain Ageing
Psychiatry, UNSW Sydney

9399 1064


Dr Karen Mather completed her first BSc (Biochemistry Honours) at La Trobe University, before finishing a Graduate Diploma in Psychology at Charles Sturt University.  She finished her second BSc (Psychology Hons) at the Australian National University in Canberra, where she then completed her PhD in Psychology examining whether telomere length is a biomarker of ageing. Since then she has held a research position at the Centre for Health Brain Ageing, including holding an Alzheimer’s Australia Postdoctoral Fellowship. During this time, she played a key role in the establishment of the Genetics & Epigenomics Group, which she now leads.  Her group includes a number of senior and junior staff and postgraduate and graduate students. At the end of 2017 Dr Mather joined NeuRA as a Senior Research Scientist, where her main research focus is to gain a better understanding of the genetic, epigenetic and environmental factors involved in ageing and age-related disease, including dementia. Current research by her group is being undertaken using large population cohorts of older adults from Australia and around the world.  Ultimately, her research aims to prevent, delay or treat age-related decline and disease and to promote healthy ageing.

Projects Dr Karen Mather is currently involved with

CURRENT PROJECTS

Genetics and Epigenetics of exceptional longevity

Dr Mather research in this project is aimed at discovering the genetics and epigenetics behind how and why certain people are able to live exceptionally long.

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Genetics and Epigenetics of exceptional longevity

Non-coding RNAs and Alzheimer’s disease

In this project, Dr Mather aims to research non-coding RNA, which is a functional RNA molecule that is transcribed from DNA but not translated into proteins and its relationship to Alzheimer’s

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Non-coding RNAs and Alzheimer’s disease

Social Cognition and Ageing

Dr Karen Mather investigates the changes that may occur in social cognition as people age. Social Cognition is a sub-topic of social psychology that focuses on how people process, store, and apply information about other people and social situations,

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Social Cognition and Ageing

Transcriptomics of the Ageing brain

Dr Mather aims to use the transcriptome, the sum total of all the messenger RNA molecules expressed from the genes of an organism, and investigate its association with the ageing brain.

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Transcriptomics of the Ageing brain

Genetics of Alzheimer’s

In this project, Dr Mather aims to research the genetics of Alzheimer’s disease and vascular cognitive impairment.

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Genetics of Alzheimer’s

Epigenetic and Environmental Factors Contributing to Ageing-Related Phenotypes

By using the discordant identical twin model, Dr Karen Mather aims to discover the epigenetic and environmental factors contributing to ageing-related phenotypes.

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Epigenetic and Environmental Factors Contributing to Ageing-Related Phenotypes

RESEARCH TEAM

DR HELEN WU PhD Student

MARY REVELAS PhD Student

DR ADITH MOHAN PhD Student

JESSICA LAZARUS PhD Student

DR DEBJANI DAS Postdoctoral Researcher

SRI CHANDANA KANCHIBHOTLA Research Assistant

DR SUMANGALI GOBHIDHARAN Research Officer

DR ANBUPALAM THALAMUTHU Lecturer