Assoc Prof Melissa Green

TEAM LEADER PROFILE

Conjoint Principle Research Scientist, NeuRA

+612 9399 1626


My research is broadly focused on determining modifiable risk factors for the development of psychosis and mood disorders, using a combination of techniques from cognitive psychology, neuroscience, genetics, and more recently epidemiology. Major funded research themes include ‘imaging genetics’ investigations of psychotic and mood disorders, and population-level research to determine the interaction of biological and environmental risk factors for psychotic disorders over the life course. My early research focused on cognitive and emotion regulation disturbances in a variety of psychiatric disorders and high risk populations, and was translated into social cognitive remediation tools used increasingly in standard psychiatric care. I am now focusing my efforts on large, well characterised clinical and population samples where possible, to faciliate the integrated study of social and biological determininants of psychosis and related conditions. I am particularly interested in stress-related biological changes that may operate differently in response to stressors experienced at different developmental stages. These projects are conducted in close collaboration with NSW government partners and colleagues at Neuroscience Research Australia (NeuRA), the Black Dog Institute, and the UNSW School of Psychology, with other national collaborators at the University of Newcastle, Monash University, the University of Melbourne, and Macquarie University. I also collaborate with researchers at the University of Leiden (The Netherlands), and the Ludwig-Maximilians-University of Munich (Germany).

Projects Assoc Prof Melissa Green is currently involved with

CURRENT PROJECTS

Epigenetic and childhood trauma in psychotic and mood disorder

This project examines epigenetic (methylation) markers of childhood trauma in schizophrenia and bipolar disorder patients.

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Epigenetics and childhood trauma

The intergenerational transmission of criminal offending behaviours

Embedded within the NSW Child Development Study, this project examines the prevalence and correlates of behavioural problems among children born to parents with and without criminal offending histories.

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The intergenerational transmission of criminal offending behaviours

Targeting early contact with the criminal justice system in young people

Embedded within the NSW Child Development Study, this project aims to identify early life risk factors, developmental mediators and outcomes associated with criminal justice system contact for young people.

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Targeting early contact with the criminal justice system in young people

Determinants of risk and resilience in multi-agency administrative records: A population record-linkage study.

Embedded within the NSW Child Development Study, this project aims to determine dynamic ‘risk’ and ‘resilience’ states in maltreated children at ages 5 and 11 years, and the likelihood of transition between these states over time, in the context of other risk and protective factors.

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Determinants of risk and resilience in multi-agency administrative records: A population record-linkage study.

Identifying new targets for primary school mental health interventions using population data

Embedded within the NSW-CDS, this project evaluates the extent to which existing school-based mental health promotion and early intervention programs modify the expression of risk profiles for psychotic, mood, and behavioural disorders in middle childhood at an individual and population level.

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Identifying new targets for primary school mental health interventions using population data

NSW Child Development Study

This project established the NSW-CDS and aims to identify vulnerability and resilience factors emerging from birth to 11 years of age, that relate to the development of mental illness and other adverse outcomes in adolescence and adulthood.

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NSW Child Development Study

Epistatic genetic effects on brain structure in schizophrenia

This project uses data from the Australian Schizophrenia Research Bank to determine interactive genetic effects on brain structure and cognition in schizophrenia.

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Epistatic genetic effects on brain structure in schizophrenia

Childhood trauma and inflammatory markers

This project examines immune and stress response markers in association with epigenetic markers and brain structure/function in psychotic disorders.

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Childhood Trauma and Inflammatory Markers

Imaging Genetics in Psychosis Study

The Imaging-Genetics in Psychosis study aims to determine common stress-related pathology among schizophrenia and bipolar disorder patients, in association with shared genetic vulnerabilities, cognitive deficits, and brain phenotypes.

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Imaging Genetics in Psychosis Study

Schizotypal personality traits and striatal function

This study tests the relationship among probabilistic association learning , schizotypal personality traits, striatal function and genes important to striatal function.

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Schizotypal personality traits and striatal function

RESEARCH TEAM

LEAH GIRSHKIN PhD Student

STACY TZOUMAKIS Lecturer

NINA TEROGANOVA PhD Student

YANN QUIDE Postdoc Fellow

DR KRISTIN LAURENS Senior Research Scientist

JESSECA ROWLAND PhD Student

KIMBERLIE DEAN Principle Research Scientist

FELICITY HARRIS Research Officer

PROF VAUGHAN CARR Senior Principle Research Scientist