Nicole Ee

NHMRC Centre of Research Excellence in Cognitive Health

The Centre of Research Excellence in Cognitive Health focuses on the integrally linked areas of optimising cognitive health and the prevention of cognitive decline.

The centre aims to:

• Build the evidence base in cognitive health promotion and prevention of cognitive decline, focussing on evaluating putative new risks and under researched areas
• Develop methods of transferring, translating and implementing established findings, through the development and evaluation of interventions
• Model population level impacts of cognitive impairment and risk modification to quantify potential economic benefits of risk reduction and to inform policy.

The CRE Cognitive Health led by Professor Kaarin Anstey is a collaboration between Chief and Associate Investigators from the Australian National University, University of Melbourne, University of New South Wales, Australian Catholic University, Baker IDI Heart and Diabetes Institute and University of Exeter.

For more information about the CRE Cognitive Health, please visit the centre website, including more information on research themes, news and events, and recent publications.

The CRE Cognitive Health is funded by the National Health and Medical Research Council.

The Dementia Risk Factors and Assessment (DemRisk) program

The Dementia Risk Factors and Assessment (DemRisk) program involves over ten years of research performed by the Anstey group on the identification and assessment of risk factors for Dementia.

The DemRisk program includes:

• Systematic reviews and meta-analyses of dementia risk and protective factors
• Analysis of cohort studies to identify dementia risk and protective factors
• Development of evidence-based interventions for dementia risk reduction
• Development of innovative e-learning resources to support dementia risk reduction
• Development of risk assessment tools validated for assessing individual exposure to risk factors known to be associated with an increased risk of developing dementia
• Development of guidelines (e.g. physical activity guidelines) to reduce risk of cognitive decline and dementia in collaboration with other researchers and organisations including the World Health Organisation
• Training of early career researchers with a focus on identifying and targeting dementia risk

Read Professor Kaarin Anstey and Dr Ruth Peters’ recent invited commentary on second-hand smoke as an under-recognised risk factor for cognitive decline here. You can also watch Professor Anstey’s NeuRAtalk on ageing well to reduce your risk of dementia here.

ARC Centre of Excellence in Population Ageing Research

The ARC Centre of Excellence in Population Ageing Research (CEPAR) is a unique collaboration bringing together academia, government and industry to address one of the major social challenges of the twenty first century. Based at the University of New South Wales with nodes at the Australian National University, The University of Melbourne, The University of Sydney and The University of Western Australia, CEPAR is producing world-class research on population ageing. CEPAR includes cross-disciplinary experts drawn from actuarial science, demography, economics, epidemiology, psychology and sociology. The Centre’s diverse research program which will deliver comprehensive outcomes with the potential to secure Australia’s future as a well-informed nation with world-best policy and practice for an ageing demographic.

Professor Anstey and Professor Mike Keane lead the CEPAR research stream concerned with decision making, expectations and cognitive ageing.

This research stream aims to:

• Develop a comprehensive model of ageing and decision making including identification of typologies of decision makers
• Develop multidisciplinary paradigms and predictive models of decision making and ageing
• Develop and evaluate interventions to increase positive expectations about ageing
• Develop life-cycle models that incorporate investments in health and housing as well as cognitive limitations in ageing.

For more information on CEPAR visit the centre website.

CEPAR has been funded primarily by the Australian Research Council, with generous support from the collaborating universities and partner organisations.

International Research Network on Dementia Prevention

Globally, dementia cases are increasing at a rate of 21 per cent annually, and most of these are occurring in low to middle-income countries. With no cure for neurodegeneration or the diseases that cause dementia, there is an urgent need to link both knowledge translation and researchers more closely together in a global effort to tackle prevention more effectively.

Founded in 2017, the International Research Network on Dementia Prevention (IRNDP) is a multinational network bringing together researchers who are working to reduce the risk of dementia across the world.

IRNDP aims to:

• Increase dementia risk reduction messaging worldwide
• Develop targeted research to answer questions about the detailed impact of known and emerging risk factors in preventing dementia
• Welcome membership from researchers in both high and low or middle income countries
• Collaborate and work closely with public health stakeholders, policy makers and those who have a diagnosis of dementia and carers.

The goals of the IRNDP have particular relevance in low- to middle-income (LMIC) countries as exposure to lifestyle and clinical risk factors becomes more common as LMIC economies grow.

While there are many current overlapping public health, patient, research, policy and practice initiatives aimed at prevention or treatment of dementia, IRNDP is the first single collaborative network of researchers to focus attention on prevention that is truly global.

For further information, visit the IRNDP website, including news and updates, an evidence hub on cohort studies, an evidence synthesis on clinical trials, and information on how to join the network.

IRNDP is chaired by Professor Kaarin Anstey and is a project of the Dementia Centre for Research Collaboration funded by the NHMRC National Institute for Dementia Research (NNIDR).

World Heath Organisation (WHO) Guidelines for the reducing the risk of cognitive decline and dementi

Systematic review of reviews were conducted to synthesize the available evidence for interventions for risk factors associated with cognitive declines and dementia. This research was used to inform WHO guideline development.