Senior Principal Research Fellow, NeuRA
Conjoint Professor of Geriatric Medicine, UNSW
+612 9399 1054
Professor Tony Broe graduated in social science (Anthropology, Geography) and Medicine from the University of Sydney. He trained in General Medicine, Geriatric Medicine and Neurology in Sydney, Glasgow and the Mayo Clinic (1966 to 1973). He was head of the University Clinical School and the Department of Neurosciences at Lidcombe Hospital (1975 to 1985); Prof of Geriatric Medicine at Concord Hospital and University of Sydney (1985 to 1999) and University of NSW (1999-2016). He has published some 200 papers, 20 Book Chapters and 4 Books on neuroepidemiology, neurodegenerative disorders and Aboriginal health & ageing. He has set up Health Services in Neurosciences, Aged Care, Community Health & Aboriginal Health. Tony is currently SPRF at Neuroscience Research Australia (2000 to 2016).
GAIL DAYLIGHT Aboriginal Dementia Education Officer (PT)
SHARON WALL Dementia Education Officer (PT)
SANDRA FORSTER Admin Officer (PT)
DR KYLIE RADFORD Project Officer and Postdoctoral Fellow
Parkinson's disease (PD) is a degenerative neurological condition, associated with cardiovascular dysfunction. Many studies have utilised heart rate variability (HRV) to assess the autonomic nervous system in PD, but blood pressure variability (BPV) has received less attention. The purpose of the present study was to compare HRV and BPV between participants with established PD, extrapyramidal motor slowing (EPMS) (not reaching clinical criteria for PD), older healthy controls (OHC), and young healthy controls (YHC), in order to ascertain whether either of these measures can be used as an early marker of non-motor symptoms in PD.
To investigate the relationship between SORL1 gene variants with ADrelated brain morphologies and AD, testing for sex-specific effects. The results provide evidence that the association of polymophisms in the sortilin-related receptor gene (SORL1) with AD and its MRI biomarkers of brain and hippocampal atrophy are moderated by sex.
This paper details our protocol for a population-based study in collaboration with local Aboriginal community organizations. The study will provide the first available prevalence rates for dementia and cognitive impairment in a representative sample of urban Aboriginal people, across city and rural communities, where the majority of Aboriginal Australians live. It will also contribute to improved assessment of dementia and cognitive impairment and to the understanding of social determinants of successful aging, of international significance.