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Tasnim attained a Bachelor of Advanced Science at the University of Sydney, with Honours in Physiology (Neuroscience) in 2013. She was awarded a summer scholarship to study cofilin aggregates in the progression of Alzheimer’s disease at the Brain and Mind Research Institute, where she continued as a Research Assistant and published a paper. Tasnim is now pursuing a PhD project looking to establish developmental neurobiological changes in the maternal-immune-activated model of schizophrenia.
Studying the molecular basis of raloxifene (a SERM) modulation of dopamine signalling in schizophrenia, which uses a maternal immune activation rodent model of schizophrenia to better understand how raloxifene brings about its effects.
CAITLIN MURPHY PhD student
DR DUNCAN SINCLAIR Postdoctoral Fellow
DEBORA ROTHMOND Senior Research Assistant
SHAN-YUAN TSAI-CHIN PhD student
DANNY BOERRIGTER Research assistant
ROXANNE CADIZ Technical assistant
YIRU ZHANG PhD student
KATE NAUDE Research assistant
JUAN OLAYA PhD student
DR MARI KONDO Postdoctoral Fellow
HELEN CAI PhD student
We sought further understanding of the significance of cofilin rods/aggregates to the disease process: Do rods/aggregates correlate with AD progression and the development of hallmark neurofibrillary tangles and neuropil threads? Are cofilin rods/aggregates found in the same neurites as hyperphosphorylated tau? Cofilin rods and aggregates signify events initiated early in the pathological cascade. Further definition of the mechanisms leading to their formation in the human brain will provide insights into the cellular causes of AD.